The structure of an LIM-only protein 4 (LMO4) and Deformed epidermal autoregulatory factor-1 (DEAF1) complex reveals a common mode of binding to LMO4.

LIM-domain only protein 4 (LMO4) is a widely expressed protein with important roles in embryonic development and Hoodies/Fleece breast cancer.It has been reported to bind many partners, including the transcription factor Deformed epidermal autoregulatory factor-1 (DEAF1), with which LMO4 shares many biological parallels.We used yeast two-hybrid ass

read more

Cyclolinopeptide B methanol trisolvate

The title compound, C56H83N9O9S·3CH3OH, is a methanol trisolvate of the cyclolinopeptide cyclo(Met1—Leu2—Ile3—Pro4—Pro5—Phe6—Phe7—Val8—Ile9) (henceforth referred Wipes to as CLP-B), which was isolated from flaxseed oil.All the amino acid residues are in an l-co

read more